Abstract Central sensitization plays a pivotal role in the maintenance of chronic pain induced by chronic pancreatitis (CP). but cortical modulation of painful CP remains elusive. This study was designed to examine the role of anterior insular cortex (aIC) in the pathogenesis of hyperalgesia in a rat model of CP. CP was induced by intraductal administration of trinitrobenzene sulfonic... https://jalyttlers.shop/product-category/pizza-oven/